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产品目录

重组人PCSK9(C端HA标签)图片
产品货号:
JN0843
中文名称:
重组人PCSK9(C端HA标签)
英文名称:
Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln31-Gln152&Ser153-Gln692表达在C端带有6His/HA/AVI标签

PCSK9质量控制:>95%(还原性SDS-PAGE)

PCSK9制剂:液体

PCSK9保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于PCSK9
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.
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